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影响特发性黄斑前膜术后视力的相关因素分析

李静  杨艳  任杰  梁军  谷威   

  1. 100021北京爱尔英智眼科医院
  • 收稿日期:2018-03-26 出版日期:2019-07-25 发布日期:2019-07-30
  • 通讯作者: 杨艳,Email:yyv2003@163.com

Associations analysis for postoperative visual acuity in idiopathic epiretinal membrane

LI Jing, YANG Yan, REN Jie, LIANG Jun, GU Wei.   

  1. Beijing Aier-Intech Eye Hospital, Beijing 100021, China
  • Received:2018-03-26 Online:2019-07-25 Published:2019-07-30
  • Contact: YANG Yan, Email: yyv2003@163.com

摘要:

 目的 探讨特发性黄斑前膜(idiopathic epiretinal membrane,iERM)术后视力的影响因素。设计 回顾性病例系列。研究对象2015-2017年特发性黄斑前膜行玻璃体手术治疗者69例(69眼)。方法 回顾病历系统,采集患者年龄、性别、既往糖尿病与高血压病史、主诉病史时间以及术前1周内及术后1、3个月的最佳矫正视力(best corrected visual acuity,BCVA)(LogMar)资料。相干光断层扫描(optical coherence tomography,OCT)测量的黄斑区6 mm直径范围的视网膜厚度,并判断外层视网膜视细胞内节椭圆体带(inner segment ellipsoid band,ISEB)完整性。术后视力的影响因素采用多元线性回归分析。主要指标 年龄、性别、既往病史、主诉病史时间、BCVA、黄斑区视网膜厚度及ISEB完整性。结果 69例患者平均BCVA术前为(0.47±0.34),术后1个月为(0.41±0.25)(t=1.77,P=0.081);术后3个月为(0.37±0.24),较术前BCVA差异有统计学意义(t=2.46,P=0.017)。黄斑中心平均视网膜厚度术前、术后1个月、3个月分别为(454.07±73.39)μm、(406.65±63.86)μm、(384.46±59.86)μm。多元线性回归分析显示,术前BCVA是影响术后3个月BCVA的主要因素(β=2.55, P=0.015),与年龄、既往糖尿病与高血压病史、主诉病史时间、术前ISEB完整性、术前黄斑各分区的视网膜厚度无显著相关。结论 特发性黄斑前膜患者术后视力主要与术前视力相关,合理的早期手术干预可能是维持黄斑前膜患者良好视力的有效治疗方式。(眼科,2019,2 8: 269-272)

关键词: 特发性黄斑前膜, 玻璃体切除术, 视力

Abstract:

 Objective To investigate the associated factors of postoperative visual acuity in idiopathic epiretinal membrane (iERM). Design Retrospective cases series. Participants 69 patients (69 eyes) with iERM underwent vitrectomy from January 2015 to June 2017 in Beijing Aier-Intech Eye Hospital. Methods By reviewing medical record system, the patients' age, medical history, preoperative (within 1 week before operation) and postoperative (1 month, 3 months after operation) best corrected visual acuity (BCVA) (LogMar) and images of optical coherence tomography (OCT) were retrospectively collected. The retinal thicknesses within the 6 mm diameter range of macular area were measured, and the integrity of segment ellipsoid band (ISEB) was judged on OCT images. Multivariate linear regression analysis was used to analyze the influencing factors of postoperative visual acuity. Main Outcome Measures age, gender, history of diabetes and hypertension, preoperative and postoperative BCVA, macular retinal thickness and ISEB integrity on OCT. Results The mean BCVA of 69 patients on preoperative and 1 month after surgery were 0.47±0.34, 0.41±0.25, respectively (t=1.77, P=0.081). The mean of BCVA on 3th month after surgery was 0.37±0.24, which was significantly higher than BCVA before surgery (t=2.46, P=0.017). The mean retinal thickness in the central macular area before surgery, one month after surgery, three months after surgery were 454.07±73.39, 406.65±63.86, 384.46±59.86 μm, respectively. Multiple linear regression analysis showed that BCVA of postoperative 3 months was mainly correlated with preoperative BCVA (β=2.55, P=0.015). Conclusion Postoperative visual acuity in patients with iERM is mainly related to preoperative visual acuity. Early and reasonable surgical intervention may be an effective way to maintain good visual acuity in patients with iERM. (Ophthalmol CHN, 2019, 28: 269-272)

Key words: idiopathic epirietinal membrane, vitrectomy, visual acuity